Rutgers University is part of a research team that have demonstrated a new approach which targets RNA instead of DNA. This is a new venue in cellular manipulation that may allow researchers to make temporary changes, as well as changes with greater specificity and functionality. They accomplished this using C2c2, which is an RNA-guided enzyme capable of targeting and changing RNA.
“C2c2 opens the door to an entirely new frontier of powerful CRISPR tools,” said Feng Zhang, senior author, and Core Institute Member of the Broad Institute. “There are an immense number of possibilities for C2c2 and we are excited to develop it into a platform for life science research and medicine.”
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