“The 200th installment of the RCSB PDB’s Molecule of the Month series has been published. August’s feature on explores how viruses use quasisymmetry to build large capsids out of many small subunits.
Since January 2000, this series has explored the structure and function of biomacromolecules from AAA+ Proteases to Zika Virus. Each installment includes an introduction to the structure and function of the molecule, a discussion of the relevance of the molecule to human health and welfare, and an interactive 3D view.
New features are published each month at RCSB PDB and PDB-101, with an archive of articles translated into Japanese available at PDBj. The full archive of articles provides a powerful tool for exploring biology.
Written and illustrated by David S. Goodsell, a research professor at Rutgers University, the Molecule of the Month has provided an easy introduction to the RCSB PDB for teachers and students around the world. Materials from the series have been used by many textbooks, magazine and journal articles, and other publications. His image of Ebola Virus Proteins was selected as the overall winner of the 2016 Wellcome Image Awards and highlighted by the FASEB BioArt Competition.
The Molecule of the Month article on Quasisymmetry in Icosahedral Viruses can be accessed here.
Several resources have been published at PDB-101 to help celebrate this milestone:
* Use the Quasisymmetry in Icosahedral Viruses activity page to build 3D paper models of several viruses to explore how quasisymmetry builds capsids with different sizes.
* In the poster 200 Icosahedral Viruses from the PDB (PDF), 200 icosahedral virus structures from the PDB are arranged and colored by the number of protein chains in each capsid.
* The Coloring Molecular Machinery Coloring Book highlights a subset of the many diverse structures featured by Molecule of the Month articles over the years. Download the full book or individual pages to start to color. Post completed images online with the hashtag #colormolecules, or send them firstname.lastname@example.org to be posted on RCSB PDB’s Facebook page.”
Read more here.